Guangzhou and Hong Kong are members of one family and maintain close exchanges and contacts over the years, said Guangzhou Mayor Wen Guohui
The two decades that have passed since Hong Kong's return to China have been marked by unprecedented closer economic integration and collaboration between Hong Kong and the Chinese mainland.
Southern Chinese cities of Guangzhou and Macao Special Administrative Region seek co-development at a special meeting held in Macao on June 5.
More than 200 university students from Hong Kong are expected to take on internships in Guangzhou, capital of Guangdong province, this year.
Guangdong will expand cooperation with the Hong Kong and Macao special administrative regions to develop a world-class bay area that can match New York and Tokyo, the province's governor said on Monday.